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posaconazole will increase the degree or outcome of diazepam by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Monitor.Observe Intently (one)mitotane decreases levels of diazepam by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Observe. Mitotane is a robust inducer of cytochrome P-4503A4; check when coadmini